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University of Michigan Improving in vitro fertilization

In vitro fertilization (IVF) is a process by which an egg is fertilized by sperm outside the body. The University of Michigan is improving this process by using a new method that involves a three-dimensional (3D) approach. IVF is typically a two-step process. The first step involves retrieving eggs from the ovaries and fertilizing them with sperm in a lab. The second step is to transfer the fertilized eggs, or embryos, back into the uterus. The University of Michigan’s new method, which is still in the research and development phase, uses a 3D approach in the second step. This involves creating a 3D model of the uterus and then transferring the embryos into this model. The advantage of this 3D approach is that it allows the embryos to be placed in the exact location in the uterus that is most conducive to implantation and pregnancy. This is a significant improvement over the traditional two-dimensional (2D) approach, which can result in embryos being placed in the wrong location. The University of Michigan is not the only institution working on this 3D IVF approach. Other institutions, such as the Cleveland Clinic, are also researching this method. IVF is a complex and expensive procedure, and it is not always successful. However, the University of Michigan’s new 3D approach holds promise for improving the success rate of IVF and helping more couples have the children they desire.
Gently rocking embryos while they grow during in vitro fertilization (IVF) improves pregnancy rates in mice by 22 percent, new University of Michigan research shows. The procedure could one day lead to significantly higher IVF success rates in humans.